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Our goal in this Piece is not to change your mind, rather to provide accurate and up-to-date facts and research results for those with questions or seeking more information. If you are one that does not agree with PrEP, just don’t take it, but please allow others to make informed decisions for themselves.
Everyone’s body is different and medications work differently inside of each of us. If you find yourself on the receiving end of side effects, before stopping any medication, check with your doctor for possible remedies.
When considering side effects, let’s take a look at a dual breakdown of temporary and possible long-term effects, keeping in mind that unlike someone who is HIV positive, taking PrEP is a lifestyle choice that can be changed at any moment, and then restarted at a later date, under a doctor’s care.
* Abdominal cramping,
* Back Pain,
* Weight loss
We at GMJ strongly suggest taking the first pill on a Friday night, if you don’t work weekends, so that you may manage any possible side effects. Also, for many, milk and dairy products are known to aggravate the nerves in the stomach and cause tummy troubles when beginning a PrEP routine.
* Chronic Kidney Disease
The following chart by Mark Mascolini, of The Center for AIDS, should shed some light on the issue of possible long-term side effects.
|Classic Risk Factors for Low Bone Mineral Density and Chronic Kidney Disease|
|Low Bone Density Risk Factors||Chronic Kidney Disease Risk Factors|
|Older age||Older age|
|White race||Black race|
|Asian race||Asian race|
|Female sex||Native Americans|
|Previous fragility fracture||Family history of chronic kidney disease|
|Family history of osteoporosis|
|Low estrogen or testosterone|
|Dietary and related factors|
|Vitamin D deficiency|
|Limited sun exposure|
|Low dietary calcium|
|Other conditions and medications|
|Diabetes mellitus||Diabetes mellitus|
|HCV infection||HCV infection|
|Chronic infection||High cholesterol|
|Chronic kidney disease||Hypertension|
|Corticosteroids (such as prednisone, cortisone)||Cardiovascular disease|
|Anticoagulants, anticonvulsants, antipsychotics, cyclosporines, glitazones, gonadotropin-releasing hormone agonists, methotrexate, proton pump inhibitors||Kidney stones or kidney infection; sickle-cell anemia; autoimmune disorders (such as lupus, scleroderma)|
|Sources: Centers for Disease Control and Prevention. National chronic kidney disease fact sheet 2010. Gupta SK, Eustace JA, Winston JA, et al. Guidelines for the management of chronic kidney disease in HIV-infected patients: recommendations of the HIV Medicine Association of the Infectious Diseases Society of America. Clin Infect Dis. 2005;40:1559-1585. McComsey GA, Tebas P, Shane E, et al. Bone disease in HIV infection: a practical review and recommendations for HIV care providers. Clin Infect Dis. 2010;51:937-946. Mayo Clinic. Osteoporosis. Mayo Clinic. Chronic kidney failure. National Institutes of Health. US National Library of Medicine. Medline Plus. Osteoporosis. National Institutes of Health. US National Library of Medicine. PubMed Health. Chronic kidney disease.|